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KMID : 0378019700130080101
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New Medical Journal
1970 Volume.13 No. 8 p.101 ~ p.107
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Influence of Ginseng and Sex Hormone on the Mesenteric Mast Cells of the Castrated Young Male Rats
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Abstract
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Dividing a total or 35 young Swiss albino rats, each weighing about 50 gm, into five experimental groups of seven rats normal, castrated, testosterone-administered after castration, ginseng-administered after castration, castrated after ginseng treatment and agian ginseng-administered - the author made observations of the changes happening to mesenteric tissue mast cells, with the following results.
1. In normal male rats, the total relative number of tissue mast cells of the mesentery was 29.42, and the greater part of them were of a rich granular type, the number of cells of a poor and a disrupted granular type being very small.
2. In castrated animals, the total number of tissue mast cells in the mesentery was 37.64. This is a rather increase compared with that of the normal group, but ;the ratios between the cells of each type were similar to those of the normal group.
3. In the group given testosterone after castration, the total number of tissue mast cells reached 32.56, and the rate of the appearance of cells of each type was similar to that of the normal group.
4. In the two groups - given ginseng after castration, and castrated after ginseng administration and given ginseng again the total number of tissue mast cells was 31.01 and 33.91 respectively, both of which being similar to that of the normal group (29.42).
To sum up, both testosterone and ginseng are presumed to have power to restore the deterioration due to lack of sexual hormone caused by castration in young animals. It further seems that testosterone and ginseng exercise a protective influence particularly on tissue mast cells by regulation the altered feature of them to the normal.
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KEYWORD
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